Brand Name(s): Lipitor
CAS nº: 134523-00-5
(a-TOR-va-stat-in)
What is Atorvastatin?
Atorvastatin is a drug used for lowering cholesterol and thereby preventing cardiovascular disease. This medication works by reducing the amounts of LDL (bad) cholesterol, total cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood.
Atorvastatin is also used to increase the level of HDL (good) cholesterol in your blood. These actions are important in reducing the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
With 2005 sales of US$12.9 billion under the brand name Lipitor®, it is currently the biggest selling drug in the world.
Latest News
High-dose statin before PCI decreases periprocedural MI risk
Loading or reloading with high-dose atorvastatin reduces the risk of periprocedural myocardial...
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Tuberous sclerosis complex (TSC) is an autosomal dominant tumor suppressor syndrome, characterized...
[more]Atorvastatin decreases elevated soluble CD40L in subjects at high cardiovascular risk. Atorvastatin on inflammatory markers study: a substudy of ACTFAST
The CD40/CD40 ligand plays a role in the inflammatory and prothrombotic processes in...
[more]Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis
Since previous studies have reported a beneficial effect of amlodipine and atorvastatin treatment...
[more]Atorvastatin and Celecoxib Synergistic Against Colon Cancer Cells
Atorvastatin and celecoxib synergistically induce cell cycle arrest and apoptosis in colon cancer...
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